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Fresh Frozen Facts Part 2: A Thoughtful Look at Plasma Transfusion by Dr. Caitlin Raymond
Caitlin Raymond / LinkedIn
Jul 28, 2025, 14:02

Fresh Frozen Facts Part 2: A Thoughtful Look at Plasma Transfusion by Dr. Caitlin Raymond

Caitlin Raymond, MD/PhD shared an insightful chain of posts on LinkedIn:

”Fresh Frozen Facts, Part II: FFP Is Not a Vitamin

Too often, fresh frozen plasma (FFP) is ordered as a reflex — for an elevated INR, a vague sense of bleeding risk, or simply because “it can’t hurt.”

But FFP is not a vitamin. It’s a powerful therapy with specific indications, real risks, and limited benefit when used indiscriminately.

In Part II of my plasma product series, I walk through the actual clinical scenarios where plasma works — from TTP and DIC to massive transfusion protocols and rare factor deficiencies.

We also touch on cryopoor plasma, the nuances of thawed plasma shelf life, and the essential question:

Are you treating a true factor deficiency — or just the labs?”

Read the full post here.

Caitlin Raymond, MD/PhD, has launched an educational series on Fresh Frozen Plasma (FFP), now available on her journal blog.

Enjoy the second part and make sure you do not miss all the Fresh Frozen Facts!

Fresh Frozen Facts Part 2: A Thoughtful Look at Plasma Transfusion by Dr. Caitlin Raymond

Stay tuned for updates to the series on Hemostasis Today.

Caitlin Raymond DIC FFP FFP Is Not a Vitamin Fresh Frozen Plasma Health Hematology Hemostasis Today Medicine PF24 TTP
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