Omar Adwan on G6PD Deficiency: Protecting Red Blood Cells from Oxidative Stress
Omar Adwan, Medical Laboratory Technologist of Modawah lab center, shared an insightful post on LinkedIn:
“G6PD (Glucose-6-Phosphate Dehydrogenase):
Genetic disorder that affects the enzyme responsible for protecting red blood cells from oxidative damage.
1. Normal Function: G6PD enzyme helps maintain the integrity of red blood cells by protecting them from oxidative stress.
2. Deficiency: In G6PD deficiency, the enzyme is either partially or completely inactive, making red blood cells more susceptible to oxidative damage.
Oxidative Stress: Red blood cells are vulnerable to oxidative stress, which can trigger hemolysis (red blood cell destruction).
Hemolytic Anemia: Repeated episodes of hemolysis can lead to anemia, characterized by fatigue, weakness, and shortness of breath.
Characteristic Features
1. Heinz Bodies: Small, rounded inclusions within red blood cells, composed of denatured hemoglobin.
2. Bite Cells: Red blood cells with a ‘bitten’ appearance, resulting from the removal of Heinz bodies by the spleen.
3. Blister Cells: Red blood cells with a characteristic ‘blister’ or vacuole.
4. Reticulocytosis: An increased production of red blood cells by the bone marrow to compensate for the loss of red blood cells due to hemolysis.
Triggers
1. Infections: Certain infections can trigger hemolysis in individuals with G6PD deficiency.
2. Medications: Certain medications, such as antimalarials or sulfonamides, can induce hemolysis.
3. Foods: Some foods, like fava beans, can trigger hemolysis”
Stay updated with Haemostasis Today.
-
Oct 3, 2025, 07:53Pancytopenia in Pregnancy: A Time-Critical Hematological Emergency
-
Oct 2, 2025, 14:12Helen McPherson at ISFP-IFRS 2025: Fibrin Clot Structure and Function Modulation by Targeting Fibrinogen aC Region
-
Oct 2, 2025, 10:48Kanishk Kumar: TFPI Market Size - Advancing Hemostasis and Antithrombotic Therapy
-
Oct 2, 2025, 07:31Non-Invasive Management of Radial Artery Pseudoaneurysm
-
Oct 2, 2025, 07:28Mohamed Gamal: Rethinking The Standard of Care for Deep Vein Thrombosis Management
-
Oct 3, 2025, 14:00Quentin Van Thillo Shares His Latest Article on VWD: Grateful to Have Worked with Cedric Hermans
-
Oct 3, 2025, 13:40Cihan Ay and Colleagues on Thromboembolism and Bleeding in Multiple Myeloma
-
Oct 3, 2025, 13:27Laura Haynes: This Was Such a Fun and Collaborative Project to Be a Part of!
-
Oct 3, 2025, 12:40Christian Pfrepper and Team's Letter on Emicizumab Plasma Concentration Measurment in EDTA plasma
-
Oct 3, 2025, 12:00Giuseppe Lippi and Colleagues on the Impact of Hemolysis on Coagulation Testing
-
Oct 3, 2025, 15:31Anirban Sen Gupta and Andrew Shoffstall Collaboration on Bioinspired Synthetic Platelet Systems for Brain Injury Treatment
-
Oct 3, 2025, 15:07Shai Shen-Orr: Excited to Share that The Human Immunome Project (HIP) Has Launched Its Scientific Partner Network
-
Oct 2, 2025, 04:59Caterina Casari - Prizes for Innovators 2025 Winner!
-
Oct 2, 2025, 04:572025 Innovators Award: Ile de France Région Recognizes 3 Researchers Who Have Committed Themselves to The Innovation
-
Oct 1, 2025, 15:59Anirban Sen Gupta: Thrilled to share a great collaboration story in Nature Portfolio
-
Oct 3, 2025, 14:48Maha Othman - Elected as the Co-Lead for the Basic and Translational Research Platform at CanVECTOR Research Network
-
Oct 3, 2025, 14:41Maria Elisa Mancuso: A Real Pleasure to Participate in The Policy Roundtable on Future of Haemophilia Care in Egypt
-
Oct 2, 2025, 04:37Louise Bannon: Did You Know that 1 in 4 People Lose Their Lives to Blood Clot-Related Conditions?
-
Oct 1, 2025, 16:35World Thrombosis Day 2025․ 8 Ways to Take Control and Save Lives
-
Oct 1, 2025, 12:30World Stroke Academy "Antithrombotic Therapy for Atherosclerotic Stroke Prevention" Webinar is Now Available to Record