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Alejandro González Veliz: Most Reported Aspirin Allergies Are Not True Hypersensitivity
Jun 9, 2026, 17:51

Alejandro González Veliz: Most Reported Aspirin Allergies Are Not True Hypersensitivity

Alejandro González Veliz, Interventional Cardiologist at Institute of Cardiology and Cardiovascular Surgery, shared a post on LinkedIn about recent article by Silvia Grimaldi et al., published in European Heart Journal, adding:

Aspirin remains one of the most important drugs in cardiovascular medicine.

Yet many patients arrive with a history of ‘aspirin allergy,’ often leading clinicians to avoid a therapy that may be crucial after PCI, ACS, or valve interventions.

The reality?

Most reported reactions are not true hypersensitivity.

A careful history can distinguish intolerance from genuine allergy, and for selected patients, aspirin desensitization can safely restore access to guideline-directed therapy.

Understanding this distinction may prevent treatment delays, suboptimal antiplatelet strategies, and potentially avoidable cardiovascular events.”

Title: Aspirin hypersensitivity: a practical guide for cardiologists

Authors: Silvia Grimaldi, Paola Migliorini, Ilaria Puxeddu, Roberta Rossini, Raffaele De Caterina

Alejandro González Veliz

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