Daniele Sannipoli: Beyond Thrombosis Prevention in Polycythaemia Vera
Daniele Sannipoli, Medico specialista – Ematologia at Ospedale San Raffaele, shared a post on LinkedIn about a recent article by Tiziano Barbui et al, published in BJHaem, adding:
“It is time to move beyond a management strategy in polycythaemia vera focused solely on cardiovascular risk.
Thrombosis prevention remains essential, but disease biology may also help guide treatment decisions.
JAK2V617F allele burden, leukocytosis and the neutrophil to lymphocyte ratio are among the features worth considering.
This study adds to the growing evidence that low dose ropeginterferon can deepen molecular responses, even in low risk PV.
A more personalised approach could combine cardiovascular risk reduction with the goal of modifying the underlying disease.”
Title: Long-term deepening of JAK2V617F molecular response with low-dose ropeginterferon in low-risk polycythaemia vera
Authors: Tiziano Barbui, Arianna Ghirardi, Francesca Fenili, Daniele Sannipoli, Giulia Benevolo, Giuseppe G. Loscocco, Annalisa Condorelli, Valerio De Stefano, Elisa Rumi, Massimiliano Bonifacio, Novella Pugliese, Alessandra Iurlo, Francesca Palandri, Andrea Patriarca, Giuseppe Carli, Marco Brociner, Paola Guglielmelli, Alessandro Rambaldi, Alessandro M. Vannucchi
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