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Ivan Budnik Highlights New Framework for Thrombus Resolution Analysis in Mouse IVC Stenosis Model
Sep 14, 2025, 12:37

Ivan Budnik Highlights New Framework for Thrombus Resolution Analysis in Mouse IVC Stenosis Model

Ivan Budnik, Postdoctoral Research Scholar at The University of Iowa, shared a post on LinkedIn:

“Our new article has just been published in RPTH Journal:

Methodological framework and unified metrics for thrombus resolution analysis in the mouse IVC stenosis model

In this study, we present a framework that combines:

  • back-branch ligation to improve model consistency,
  • longitudinal MRI for volumetric tracking, and
  • unified resolution metrics – proportional resolution rate and time to half-maximum thrombus volume.

We hope these standardized measures will facilitate cross-study comparisons and strengthen preclinical evaluation of therapies that promote venous thrombus resolution.

Grateful to Dr. Anil Chauhan for leading this project and to my co-authors Dr. Mariia Kumskova and Dr. Daniel Thedens for their expertise and great collaboration!”

Title: Methodological framework and unified metrics for thrombus resolution analysis in the mouse inferior vena cava stenosis model

Authors: Ivan Budnik, Mariia Kumskova, Daniel Thedens, Anil K. Chauhan

Ivan Budnik

Read the full paper here.

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