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Ivan Budnik Highlights New Framework for Thrombus Resolution Analysis in Mouse IVC Stenosis Model
Ivan Budnik /LinkedIn
Sep 14, 2025, 12:37

Ivan Budnik Highlights New Framework for Thrombus Resolution Analysis in Mouse IVC Stenosis Model

Ivan Budnik, Postdoctoral Research Scholar at The University of Iowa, shared a post on LinkedIn:

“Our new article has just been published in RPTH Journal:

Methodological framework and unified metrics for thrombus resolution analysis in the mouse IVC stenosis model

In this study, we present a framework that combines:

  • back-branch ligation to improve model consistency,
  • longitudinal MRI for volumetric tracking, and
  • unified resolution metrics – proportional resolution rate and time to half-maximum thrombus volume.

We hope these standardized measures will facilitate cross-study comparisons and strengthen preclinical evaluation of therapies that promote venous thrombus resolution.

Grateful to Dr. Anil Chauhan for leading this project and to my co-authors Dr. Mariia Kumskova and Dr. Daniel Thedens for their expertise and great collaboration!”

Title: Methodological framework and unified metrics for thrombus resolution analysis in the mouse inferior vena cava stenosis model

Authors: Ivan Budnik, Mariia Kumskova, Daniel Thedens, Anil K. Chauhan

Ivan Budnik

Read the full paper here.

Find more posts on Hemostasis Today.

Anil K. Chauhan Daniel Thedens Hematology Hemostasis Hemostasis Today Ivan Budnik IVC stenosis Mariia Kumskova Medicine RPTH Journal thrombosis thrombus Thrombus Resolution
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