Jan Sloves։ Pedal Venous Maturation Predicts Limb Salvage in No‑Option CLTI
Jan Sloves, President and Consultant at Vascular Imaging Professionals LLC shared Jill Sommerset’s post on LinkedIn, adding:
”Excellent Manuscript By Jill Sommerset and Colleagues
‘Pedal Venous Maturation (PVM) shows up in most of these no‑option CLTI limbs and it’s time‑dependent, about 86% have it by 6 months, and once it appears, it sticks, even if the conduit closes.’
‘PVM is the signal that matters: every patient who developed PVM healed and kept their limb; every patient who didn’t went on to major amputation.’
‘Conduit patency alone is misleading – two‑thirds of the amputees still had a patent VA, while patients with PVM often did fine even after occlusion because the distal venous bed had already remodeled.’
‘A structured pedal duplex exam lets you actually watch maturation happen: venous PSV/EDV climb, RI stays low, and pedal acceleration time improves in the arteries.’
‘Follow up after VA needs to move away from ‘is the stent open?’ and toward ‘is the foot physiologically matured?’ using PVM and pedal acceleration time as the key duplex endpoints.’ ”
Jill Sommerset, Co-Founder / CSO at Moonrise Medical, shared a post on LinkedIn, about a recent article she and her colleagues co-authored, published in European Journal of Vascular and Endovascular Surgery:
”Pleased to share our work demonstrating how duplex ultrasound and pedal venous maturation can predict outcomes following deep venous arterialization (DVA) in no-option chronic limb-threatening ischemia (CLTI) patients.
These findings reinforce that ultrasound is not simply a post-procedural surveillance tool, but a physiologic guide for assessing hemodynamic success after DVA. The accompanying image illustrates post-DVA positive pedal venous maturation in a previously ‘desert foot,’ where color Doppler demonstrates restoration of flow within the terminal pedal venous system and measurable venous Pedal Acceleration Time (vPAT = 75 ms), reflecting meaningful hemodynamic improvement.
Grateful to my co-authors Miguel Montero Baker, Joseph R. Steele, Jeffrey Hull, Mary Costantino, John Rundback and collaborators.
Proud of the continued role ultrasound plays in advancing limb preservation for this complex patient population…”
Proceed to the video attached to the post.
Title: Pedal Venous Maturation on Duplex Ultrasound Predicts Outcomes after Venous Arterialisation in No Option Chronic Limb Threatening Ischaemia
Authors: Jill Sommerset, Jeffrey Hull, Joseph R. Steele, Guillermo Elizondo-Riojas, John H. Rundback, Mary Costantino, Miguel Montero-Baker
Read the Full Article on European Journal of Vascular and Endovascular Surgery.
More posts from Jan Sloves on Hemostasis Today.
-
Mar 25, 2026, 16:00Randa Bascharon: When to Consider Wharton’s Jelly in Tendon, Ligament, and Joint Conditions
-
Mar 25, 2026, 15:56Boris Pasche: Karmanos Cancer Institute Leads Innovation in Cancer and Hematologic Disease Treatment
-
Mar 25, 2026, 15:52Indunil Karunarathna: Kawasaki Disease at the Intersection of Immunology, Cardiology, and Vascular Biology
-
Mar 25, 2026, 15:48Micah Grey: Reflecting on an Incredible Experience at the THSNA Congress
-
Mar 25, 2026, 15:45Christi Miller: Exploring Key Facts about Hemophilia During Bleeding Disorders Awareness Month
-
Mar 25, 2026, 15:44Stéphane Laurent: Why the Relationship Between AfSBT and ISBT Matters in Blood Management
-
Mar 25, 2026, 15:36Seema Dawood: EDTA-Induced Platelet Satellitism
-
Mar 25, 2026, 15:35ABO-Incompatible Transfusions and Severe Allergic Reactions – ISBT
-
Mar 25, 2026, 15:14Critical Gaps in AF Stroke Prevention – JTH