Understanding Natural Anticoagulant Deficiencies – JTH
Journal of Thrombosis and Haemostasis (JTH) shared a post on LinkedIn about a recent article by Katarzyna Mayger et al., adding:
“Physiological anticoagulant deficiencies: pathogenesis, diagnosis, and clinical implications
Deficiencies of antithrombin, protein C, and protein S raise thrombosis risk but remain tricky to diagnose.
This review explains current testing, from chromogenic activity assays to free protein S antigen, and the pitfalls of assay variability and treatment interference.
The authors expect multi-gene thrombophilia panels to support more personalized diagnosis as access improves.”
Title: Physiological anticoagulant deficiencies: pathogenesis, diagnosis, and clinical implications
Authors: Katarzyna Mayger, Christelle Orlando, Beverley J. Hunt
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