Lucia Härtel: Exercise, IL-10 Signaling, and Post-Stroke Brain Plasticity
Lucia Härtel, Resident Physician at LWL-Klinik Münster, shared on LinkedIn about a recent article by A. Schmidt-Pogoda et al, published in Nature Communications, adding:
”One of the most underrated interventions in stroke recovery might already be available to every patient: exercise.
A recent study from our research group at University Hospital Münster, published in Nature Communications, showed that physical activity facilitates post-stroke recovery by reducing neuronal hyperexcitability; mediated through IL-10 signaling. In other words: exercise doesn’t just help patients feel better.
It changes the brain at a molecular level.
Having spent 16 months on a stroke unit, I’ve seen firsthand how much the gap between bench and bedside still matters.
Translational research like this is what bridges it.
What excites me most: findings like these open doors not just for rehabilitation, but for entirely new therapeutic targets in stroke recovery.
Curious what others think: are we doing enough to integrate exercise science into neurological treatment protocols?”
Title: Exercise facilitates post-stroke recovery through mitigation of neuronal hyperexcitability via interleukin-10 signaling
Authors: A. Schmidt-Pogoda, T. Ruck, JK Strecker, M. Hoppen, L. Fazio, L. Vinnenberg, B. Maus, L. Wachsmuth, M. Cerina, K. Diederich, S. Lichtenberg, H. Abberger, LAL Haertel, D. Schafflick, G. Meyer zu Hörste, AM Herrmann, P. Hundehege, V. Narayanan, C. Nelke, K. Kruithoff, J. Bosbach, E. Vicari, T. Ramcke, C. Beuker, E. Hadaschik, T. Budde, C. Faber, H. Wiendl, W. Hansen, SG Meuth, J. Minnerup
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