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Lucia Härtel: Exercise, IL-10 Signaling, and Post-Stroke Brain Plasticity
Lucia Härtel/LinkedIn
Jun 7, 2026, 22:11

Lucia Härtel: Exercise, IL-10 Signaling, and Post-Stroke Brain Plasticity

Lucia Härtel, Resident Physician at LWL-Klinik Münster, shared on LinkedIn about a recent article by A. Schmidt-Pogoda et al, published in Nature Communications, adding:

”One of the most underrated interventions in stroke recovery might already be available to every patient: exercise.

A recent study from our research group at University Hospital Münster, published in Nature Communications, showed that physical activity facilitates post-stroke recovery by reducing neuronal hyperexcitability; mediated through IL-10 signaling. In other words: exercise doesn’t just help patients feel better.

It changes the brain at a molecular level.

Having spent 16 months on a stroke unit, I’ve seen firsthand how much the gap between bench and bedside still matters.

Translational research like this is what bridges it.

What excites me most: findings like these open doors not just for rehabilitation, but for entirely new therapeutic targets in stroke recovery.

Curious what others think: are we doing enough to integrate exercise science into neurological treatment protocols?”

Title: Exercise facilitates post-stroke recovery through mitigation of neuronal hyperexcitability via interleukin-10 signaling

Authors: A. Schmidt-Pogoda, T. Ruck, JK Strecker, M. Hoppen, L. Fazio, L. Vinnenberg, B. Maus, L. Wachsmuth, M. Cerina, K. Diederich, S. Lichtenberg, H. Abberger, LAL Haertel, D. Schafflick, G. Meyer zu Hörste, AM Herrmann, P. Hundehege, V. Narayanan, C. Nelke, K. Kruithoff, J. Bosbach, E. Vicari, T. Ramcke, C. Beuker, E. Hadaschik, T. Budde, C. Faber, H. Wiendl, W. Hansen, SG Meuth, J. Minnerup

Lucia Härtel: Exercise, IL-10 Signaling, and Post-Stroke Brain Plasticity

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A. Schmidt-Pogoda AM Herrmann B. Maus C. Beuker C. Faber C. Nelke D. Schafflick E. Hadaschik E. Vicari G. Meyer zu Hörste H. Abberger H. Wiendl Health Hematology Hemostasis Hemostasis News Hemostasis Today IL-10 J. Bosbach J. Minnerup JK Strecker K. Diederich K. Kruithoff L. Fazio L. Vinnenberg L. Wachsmuth LAL Haertel Lucia Härtel M. Cerina M. Hoppen Medicine Nature Communications P. Hundehege S. Lichtenberg SG Meuth stroke T. Budde T. Ramcke T. Ruck thrombosis University Hospital Münster V. Narayanan W. Hansen
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