Nicholas Raccagni: Heparin for VTE Prevention After Traumatic Brain Injury
Nicholas Raccagni, Biomedical Research Trainee at Virgilio Program, Neurosurgery Internship at Fondazione IRCCS Istituto Neurologico Carlo Besta (Milan, Italy), shared a post on LinkedIn about a recent article he and his colleges co-authored, published in Neurosurgery, adding:
“Venous thromboembolism prophylaxis after traumatic brain injury sits at the intersection of thrombosis prevention and hemorrhagic risk.
In our recent article in Neurosurgery, we compared low-molecular-weight heparin and unfractionated heparin in adults with TBI, synthesizing the available direct comparative evidence and examining the consistency of observed associations across TBI phenotypes.
Our findings point to a clinically relevant signal, but one that remains difficult to disentangle from treatment selection and residual confounding present within the entirely retrospective evidence base.
Prospective studies are needed to determine whether this signal is causal and how it should inform thromboprophylaxis in TBI.
I am especially grateful to Leonardo Di Cosmo and Ismail Zaed for their close collaboration throughout this project, and to all my co-authors for their contributions.”
Title: Low-Molecular-Weight Heparin Versus Unfractionated Heparin for Venous Thromboembolism Prophylaxis in Adult Traumatic Brain Injury: A Systematic Review and Meta-Analysis
Authors: Nicholas Giulio Raccagni, Leonardo Di Cosmo, Marco Dotti, Filippo Emanuele Colella, Sofia Carmelini, Ismail Zaed
Stay updated on all scientific advances with Hemostasis Today.
-
Nov 8, 2026, 19:31Anna Kajaste-Rudnitski: Presenting AAV-Induced p53 Signalling in Human CNS Cells at ESGCT 26
-
Nov 8, 2026, 19:29David McIntosh: Cybersecurity Matters, but Blood Availability Remains the Bigger Challenge
-
Nov 8, 2026, 19:26Wenxue Ma: An Integrative Framework for Macrophage-Mediated Therapeutic Resistance in Cancer
-
Nov 8, 2026, 19:25Yildiz Yigit: Presenting a Polycythemia Vera Case at the MPN Subcommittee Session
-
Nov 8, 2026, 18:56Denis Oduor: Strengthening the Regulation and Delivery of Blood Transfusion and Transplantation Services
-
Nov 8, 2026, 18:28Raghavendra Rao: A Narrative Review on Chronic Venous Disease during Pregnancy
-
Nov 8, 2026, 17:57Dhiren Patel: PLD1-Derived Phospholipids Regulate NAD Kinase and ROS Production in Neutrophils
-
Nov 8, 2026, 17:48Andra T.: What Causes Antiphospholipid Syndrome? – Four Steps, not One Cause
-
Nov 8, 2026, 17:38Nasrin Samadi: Can a Normal Clotting Test Be Misleading?