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Rolando Claure: Apixaban Shows a More Favorable Benefit Risk Balance in Advanced CKD With AF
Sep 21, 2026, 00:20

Rolando Claure: Apixaban Shows a More Favorable Benefit Risk Balance in Advanced CKD With AF

Rolando Claure, Member of the Executive Committee at KDIGO, Vice President of Region 3 at SLANH – Latin American Society of Nephrology and Hypertension, Nephrologist at Renal Patient Care Unit (UNAER), shared a post on X about a recent article by Qiaoxi Chen et al, published in JAMA Network Open, adding:

“In advanced non-dialysis CKD with AF, apixaban was linked to lower ischemic stroke but higher major bleeding vs no anticoagulation.

Warfarin – higher bleeding without significant stroke reduction.

Apixaban showed a more favorable benefit–risk balance vs warfarin.”

Title: Oral Anticoagulants in Patients With Atrial Fibrillation and Advanced CKD Not Requiring Dialysis

Authors: Qiaoxi Chen, Daniel E. Singer, Edouard L. Fu, Chun-Ting Yang, Kevin Pritchard, Rishi J. Desai, Kueiyu Joshua Lin

Rolando Claure

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