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Abdul Mannan: When Gender Bias Becomes a Diagnostic Error – Inherited Bleeding Disorders are Still Being Missed
Dr Abdul Mannan/Linkedin
Jan 2, 2026, 03:52

Abdul Mannan: When Gender Bias Becomes a Diagnostic Error – Inherited Bleeding Disorders are Still Being Missed

Dr Abdul Mannan, Consultant Haematologist at Betsi Cadwaladr University Health Board, shared a post on LinkedIn:

“When Gender Bias Becomes a Diagnostic Error

Abdul Mannan: When Gender Bias Becomes a Diagnostic Error - Inherited Bleeding Disorders are Still Being Missed

Inherited Bleeding Disorders are still being missed. Not because tests don’t exist. But because thinking stops too early.

In bleeding disorders, biology is not the only barrier.
Cognitive bias is.

Same system. Same disease risk. Very different responses.

When a man presents with joint bleeding, alarms go off.
Full coagulation work-up. Factor levels. Genetics. Diagnosis.

When a woman or girl presents with heavy menstrual bleeding, the response is often very different:
“It’s normal.”
“It runs in the family.”
“It’s gynaecological.”
“Try iron. Try hormones.”
And the hood never gets opened.

These are not knowledge gaps. They are cognitive roadblocks:

  •  Normalization of symptoms
    Generational bleeding is mistaken for “family traits” rather than inherited disease.
  •  The ‘only a carrier’ myth
    Women with hemophilia genes are still assumed to be asymptomatic, despite clear evidence to the contrary.
  •  Satisfied search error

Find mild vWD → stop investigating
Miss the second defect → label as “treatment-resistant”

  •  Physiological masking
    Pregnancy normalizes factor levels → false reassurance → delayed postpartum hemorrhage.
  •  Menstrual stigma

If bleeding isn’t quantified, it isn’t taken seriously.
A pad every 30 minutes becomes “just a heavy period”.

Think of it like this:
A man with hemarthrosis gets a flashing check engine light.
A woman with HMB gets a low tyre pressure warning.
One triggers diagnostics.
The other gets a quick fix.
Until the breakdown happens — surgery, childbirth, hemorrhage.

Key message:
Treatment failure in women is not “difficult anatomy”.
It is a red flag.
What changes outcomes?

  •  Structured bleeding assessment tools
  •  Factor levels in symptomatic “carriers”
  •  Looking for combined defects
  •  Testing outside pregnancy
  •  Taking menstrual bleeding seriously — clinically, not culturally

This infographic isn’t about blame.
It’s about where our thinking stops too soon.
If we don’t challenge these cognitive shortcuts, women with inherited bleeding disorders will continue to be diagnosed late, during crises, or not at all.
Blood Doctor
Because bleeding disorders don’t respect gender — but bias still does.”

Get more insights from Abdul Mannan with Hemostasis Today.

Diagnostic Error Dr Abdul Mannan family traits Find mild vWD Gender Bias Headlines Health Hemostasis Hemostasis Today Inherited bleeding disorders Medicine thrombosis von Willebrand disease (VWD)
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