Heghine Khachatryan: Regarding Coagulation Factor Dynamics During Pregnancy in Hemophilia B Carriers
Heghine Khachatryan, Editor-in-Chief of Hemostasis Today, Head of Hemophilia and Thrombosis Center at Yeolyan Hematology and Oncology Center, shared JTH’s post on LinkedIn:
“This study provides an important and thought-provoking challenge to existing paradigms regarding coagulation factor dynamics during pregnancy in hemophilia B carriers.
The observation that antenatal FIX levels may increase—contrary to current guidance—has direct implications for risk stratification, peripartum planning, and therapeutic decision-making.
It underscores the need for individualized longitudinal monitoring rather than reliance on static baseline assumptions.
Moreover, these findings highlight a critical gap in evidence-based recommendations and reinforce the urgency of generating high-quality prospective data to inform updated clinical guidelines.
A valuable contribution toward more precise and personalized hemostatic care in women with inherited bleeding disorders.”
Journal of Thrombosis and Haemostasis (JTH) shared a post on LinkedIn about a recent article by Claire Kelly et al, published in JTH, adding:
“Engineering Bone Marrow in a Dish — A Bloody Business:
Preclinical Opportunities, Translational Use Cases, and a Call for Consensus
This review examines advances in bone marrow organoid development — integrating stem cell engineering, biomaterials, and microphysiologic systems — and proposes consensus benchmarks for an ideal ex vivo human bone marrow niche to overcome translational barriers in drug development and personalized medicine.”
Title: Contrary to current guidance, antenatal factor IX levels increase in female carriers of hemophilia B
Authors: Claire Kelly, Janet Cleary, Catriona Keenan, Isabelle Delachapelle, Leona Connolly, Mary Byrne, Mairead O’Donovan, Niamh M. O’Connell, James S. O’Donnell, Kevin Ryan, Michelle Lavin
Other posts featuring Heghine Khachatryan and JTH on Hemostasis Today.
-
Jun 24, 2026, 13:50Tijjani Balas: Why Early Detection of DVT Matters
-
Jun 24, 2026, 13:43Brandon Michael Henry: Interpreting Complement Activation After AAV Gene Therapy
-
Jun 24, 2026, 13:37Heba Youssef: Heparin-Induced Thrombocytopenia – The Prothrombotic Emergency You Cannot Miss
-
Jun 24, 2026, 13:32Jecko Thachil: Understanding the Clinical Spectrum of Vitamin B12
-
Jun 24, 2026, 13:32Namrata Singh: Beyond Low Platelets – Understanding What Triggers ITP
-
Jun 24, 2026, 09:29Advancing Women’s Health Through Collaboration with Jean Hailes for Women’s Health – Stroke Foundation
-
Jun 24, 2026, 09:18The Lasting Immunological Footprint of VITT – JTH
-
Jun 24, 2026, 09:09Umberto Pensato: Dedicated Funding Pathways for Stroke Research in Italy
-
Jun 24, 2026, 09:00Danny Gaskin: BBTS 2026 and the Evolving Role of Transfusion in Maternity Care