Illiasul Ibad/X
Aug 31, 2025, 12:39
Lupus Anticoagulant and Antiphospholipid Syndrome: Insights from Local Practice
Illiasul Ibad, Rheumatologist at Christian Medical College, posted on X:
”Lupus Anticoagulant is a Double Misnomer
It’s neither an anticoagulant nor specific to lupus.
LA are antiphospholipid antibodies that bind PL + cofactors
They prolong clotting assays (like aPTT, dRVVT) in vitro
But in vivo, they ↑ thrombotic risk!
For further reading.”
Title: Lupus Anticoagulant Testing for Diagnosis of Antiphospholipid Syndrome: A Perspective Informed by Local Practice
Authors: Emmanuel J. Favaloro, Leonardo Pasalic
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