environment.uq.edu.au
Feb 23, 2026, 17:42
Bryan Fry: First Evidence That Bothrops atrox Venom Directly Activates Human Factor VII
Bryan Fry, Professor of Toxicology at the University of Queensland, shared a post on LinkedIn, about a recent article he and his colleagues co-authored, adding:
”Highlights
- Neonate Bothrops atrox venom is far more procoagulant than adult venom on plasma and fibrinogen.
- Neonate venom activates prothrombin and Factor VII via FVa-dependent pathways more strongly than adults.
- We provide the first evidence that Bothrops atrox venom directly activates human Factor VII.
- Clinically used antivenoms neutralise adult venom better than neonate venom; Butantan performs best.
- Findings indicate high coagulopathy risk after neonate bites and support adding neonate venom to antivenom immunizing mixture.”
Title: Pirates of the coagulase: Clinical implications of dramatic ontogenetic shifts in Yellow Beard (Bothrops atrox) lancehead pitviper Factor Va-mediated venom activation of blood clotting factors
Authors: Katherine Jordan, Patrick S. Champagne, Lorenzo Seneci, Bryan G. Fry
Read the Full Article on Toxicon.
Stay updated with Hemostasis Today.
-
Jun 11, 2026, 08:35Mohamed Reda: CBC Report – More Than Just Numbers
-
Jun 11, 2026, 07:59Uday Sankar Akash Vankayala: Key Findings on IBD-Associated VTE Phenotypes and Inpatient Burden
-
Jun 11, 2026, 07:41Zia Ullah: Hidden Cerebral Venous Sinus Thrombosis After Dengue Recovery
-
Jun 11, 2026, 07:24Aaron Rodriguez Calienes: RESISTANT Registry Provides Reassuring Safety Data for Acute Intracranial Stenting
-
Jun 11, 2026, 07:17Mbunya. S. Misiani: From the WFH Congress to Meaningful Change for Patients with Bleeding Disorders Worldwide
-
Jun 11, 2026, 07:06Bernard Slater Jr.: Hemophilia B Reminds You that No Matter How Strong You Are, You Are Still Human
-
Jun 11, 2026, 05:11Daniel I McIsaac: Less Blood Loss and No Excess VTE with Tranexamic Acid in High-Risk Surgery
-
Jun 11, 2026, 05:03Aymeric Couturier: Lessons from the TRACK Trial on Anticoagulation in Advanced CKD
-
Jun 11, 2026, 04:53Umut Kocabas: Current Practice and Guideline Adherence on Cancer-Associated Thrombosis in Turkey