Søren Hough: A Bispecific siRNA Design for Simultaneous Gene Silencing in Cancer
Søren Hough, Editor, Drug Modalities and TIDES Global at BioXconomy, shared a post on LinkedIn:
“Genetics is a lot more complicated than ‘turn off Gene A, get Disease B.’
Oftentimes, genetic networks look more like logic puzzles, requiring a sometimes dizzying combination of activation, silencing, modulating, and other tweaks to achieve a particular outcome.
That’s the logic researchers in Osaka, Japan, have applied to their ‘bispecific’ siRNA design: a single molecule that can shut off two genes at once. Their goal is to tackle diseases like cancer by finding consensus regions between genes with the goal of simultaneous gene silencing. Doing so could help bypass genetic redundancies that make some cancer types resistant to treatment.
Check out my story over at BioXconomy .”
Stay updated with Hemostasis Today.
-
Aug 26, 2026, 18:06Ashkan Shoamanesh: ANNEXa-I Analyses Inform Individualized Treatment in Intracranial Hemorrhage
-
Aug 26, 2026, 18:01Sam Tsimikas: Lp(a) and Oxidized Phospholipids Reveal a New Link Between Hypercoagulability and Stronger Clot Formation
-
Aug 26, 2026, 17:52Kamlesh Darji: A Practical Guide to Interpreting Coagulation Tests
-
Aug 26, 2026, 17:46Bruno Pougault: The Hidden Burden of Hemostatic Disorders in Women
-
Aug 26, 2026, 17:39Charan Gubba: Adult ITP – A major shift in the 2026 ASH Guidelines
-
Aug 26, 2026, 17:38Stephan A Mayer: Early Imaging Reveals Higher Risk of Hematoma Expansion After ICH
-
Aug 26, 2026, 17:09Kemal Karaagac: NOACs May Offer Cognitive and Clinical Benefits in AF With Alzheimer’s Disease
-
Aug 26, 2026, 16:53Chokri Ben Lamine: Antiphospholipid Syndrome After Kidney Transplantation
-
Aug 26, 2026, 16:32Kai Rejeski: Why TP53 Mutations May Define a Higher-Risk CAR-T Population