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W. Alberto Sifuentes Giraldo: EULAR 2025 Key Recommendations for Behçet’s Syndrome Management
W. Alberto Sifuentes Giraldo/LinkedIn
Mar 25, 2026, 15:00

W. Alberto Sifuentes Giraldo: EULAR 2025 Key Recommendations for Behçet’s Syndrome Management

W. Alberto Sifuentes Giraldo, Rheumatologist at Hospital Nuestra Señora de Sonsoles (Sacyl), shared a post on LinkedIn about a recent article by Gulen Hatemi, adding:

“The 2025 update of EULAR recommendations for the management of Behçet’s syndrome, recently published in Annals of the Rheumatic Diseases, include 5 overarching principles and 12 recommendations organised by organ involvement.

Overarching principles stress the relapsing-remitting nature of the disease, individualised treatment based on activity and prognostic factors, a multidisciplinary approach, patient education, and shared decision-making.

Key recommendations:

  • Mucocutaneous and joint involvement: Colchicine is first-line; apremilast or TNFα inhibitors for refractory cases.
  • Organ-threatening disease: Early aggressive therapy with glucocorticoids and immunosuppressives, with prompt use of monoclonal TNFα inhibitors encouraged for severe or life-threatening manifestations.

Of the 12 recommendations, 1 is entirely new, 7 were modified, and 4 had only wording changes.”

Title: EULAR recommendations for the management of Behçet’s syndrome: 2025 update

Authors: Gulen Hatemi, Sofia Ramiro, Yesim Ozguler, Sinem Nihal Esatoglu, Gunnar Tomasson, Stephane Barete, Alessandra Bettiol, Bahram Bodaghi, Vladimira Boyadzhieva, Luca Cantarini, Aykut Ferhat Celik, Omar Dhrif, Georgina Ducker, Giacomo Emmi, Ahmet Gül, Jörg Henes, Ina Koetter, Martin Krusche, Giuseppe Lopalco, Robert J. Moots, David Saadoun, Carlo Salvarani, Petros Sfikakis, Aleksandra Stefanovic, Rosaria Talarico, Ilknur Tugal-Tutkun, Ugur Uygunoglu, Qianyu Zhao, Hasan Yazici

Read the Full Article on Annals of the Rheumatic Diseases.

W. Alberto Sifuentes Giraldo: EULAR 2025 Key Recommendations for Behçet’s Syndrome Management

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Ahmet Gül Aleksandra Stefanovic Alessandra Bettiol Annals of the Rheumatic Diseases Aykut Ferhat Celik Bahram Bodaghi Behçet’s Syndrome Carlo Salvarani David Saadoun EULAR Georgina Ducker Giacomo Emmi Giuseppe Lopalco Gulen Hatemi Gunnar Tomasson Hasan Yazici Ilknur Tugal-Tutkun Ina Koetter Jörg Henes Luca Cantarini Martin Krusche Omar Dhrif Petros Sfikakis Qianyu Zhao Robert J. Moots Rosaria Talarico Sinem Nihal Esatoglu Sofia Ramiro Stephane Barete TNFα inhibitors Ugur Uygunoglu Vladimira Boyadzhieva Yesim Ozguler
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