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Low-Dose Aspirin Reduces Colorectal Cancer Recurrence in PIK3CA-Mutated Patients
Sep 20, 2025, 15:45

Low-Dose Aspirin Reduces Colorectal Cancer Recurrence in PIK3CA-Mutated Patients

Flora Peyvandi, Professor of Internal Medicine-Hemostasis and Thrombosis Unit, University of Milan, former President of ISTH, shared on X:

“Low dose Aspirin led to a significantly lower incidence of colorectal cancer recurrence than placebo among patients with PIK3CA hotspot mutations in exon 9 or 20 and with a similar benefit among those with other somatic alterations in PI3K pathway genes.”

Title: Low-Dose Aspirin for PI3K-Altered Localized Colorectal Cancer

Authors: Anna Martling, Ida Hed Myrberg, Mef Nilbert, Henrik Grönberg, Fredrik Granath, Martin Eklund, Tom Öresland, Lene H. Iversen, Carola Haapamäki, Martin Janson, Karin Westberg, Josefin Segelman, Urban Ersson, Mattias Prytz, Eva Angenete, Rebecka Bergström, Markus Mayrhofer, Bengt Glimelius, Johan Lindberg

Aspirin

Read the full article here.

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