Jukka Partanen: How Blood Donation Selection Shapes the Human Genome Landscape
Jukka Partanen, Research Professor At Finnish Red Cross Blood Service, shared on LinkedIn about a recent article he and his colleagues co-authored, published in European Journal of Human Genetics, adding:
”Are blood donors a random sample from the general population, or a selected one?
Both the criteria set by blood establishments for blood donor and donor’s self-assessment (feeling fit enought to donate blood) results in a repeated selection of individual who regularly donate blood.
This is called the healthy donor effect.
We compared the genome profiles of regular blood donors of the Blood Service Biobank in Finland with other Finnish population cohorts in FinnGen and found that the healthy donor effect indeed is visible at the genome level, too.
Genetic risk variants to many common diseases had lower frequences in regular blood donors – something we must remember when applying blood donor genome data as a reference.”
Title: Genome-wide association study identifies protective genetic factors in active blood donors against multiple diseases
Authors: Jonna Clancy, Jarkko Toivonen, Jouni Lauronen, Jukka Partanen, Mikko Arvas, Jarmo Ritari
Stay updated on all scientific advances with Hemostasis Today.
-
Jun 10, 2026, 04:02Heghine Khachatryan: What Should We Test From a Hematologic Perspective in Young Cryptogenic Stroke?
-
Jun 9, 2026, 17:55Can We Prevent Postpartum Blood Clots without Putting Most Women on Heparin? – RPTH Journal
-
Jun 9, 2026, 17:54Lucky Oseghale Oloboh: Health Is Power, Health Is Personal, and Health Is Our First Responsibility in Life’s Journey on Mother Earth
-
Jun 9, 2026, 17:53Ajay Samkaria: How ABO Subgroups Directly Impact Transfusion Safety
-
Jun 9, 2026, 17:51Alejandro González Veliz: Most Reported Aspirin Allergies Are Not True Hypersensitivity
-
Jun 9, 2026, 17:50Mary Cushman: It’s Time to Apply to Be on an ISTH SSC
-
Jun 9, 2026, 15:56Wolfgang Miesbach: A New Genetic Perspective on the Worldwide Burden of von Willebrand Disease
-
Jun 9, 2026, 15:34Shanon Marie Corsino: Nationwide Insights into Cancer-Associated Thrombosis in Filipino Patients
-
Jun 9, 2026, 15:20Murtuza Ali: Types of Blood Transfusions – A Quick Clinical Guide