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Omid Seidizadeh Shares Deep Molecular Modeling and Mechanistic Insights into Type 2A VWD
Omid Seidizadeh/LinkedIn
Oct 23, 2025, 06:48

Omid Seidizadeh Shares Deep Molecular Modeling and Mechanistic Insights into Type 2A VWD

Omid Seidizadeh, Research Leader of the A. Bianchi Bonomi Hemophilia and Thrombosis Center, shared on LinkedIn:

”Happy to share our new publication in RPTH Journal

Our study integrates clinical, biochemical, and structural data to uncover how A2 domain variants drive disease through impaired multimerization, altered proteolysis, and increased clearance.

A great collaboration with Dr. Luca Mollica and the team!”

Read the full article in RPTH.

Article: Deep Molecular Modeling and Mechanistic Insights into Type 2A VWD with VWF A2 Domain Mutations

Authors: Omid Seidizadeh, Luca Mollica, Davide Giana, Luciano Baronciani, Paola Colpani, Lea Sicuro, Andrea Cairo, Flora Peyvandi

Omid Seidizadeh Shares Deep Molecular Modeling and Mechanistic Insights into Type 2A VWD

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Andrea Cairo Bianchi Bonomi Hemophilia and Thrombosis Center bleeding disorders Davide Giana Flora Peyvandi Health Hematology Hemostasis Hemostasis Today Lea Sicuro Luca Mollica Luciano Baronciani Medicine Omid Seidizadeh Paola Colpani rpth VWD VWF
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