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Zain Khalpey: The Hidden Impact of Sex Hormones on Thrombosis and Heart Health
Apr 17, 2026, 12:15

Zain Khalpey: The Hidden Impact of Sex Hormones on Thrombosis and Heart Health

Zain Khalpey, Adjunct Assistant Professor of Surgery at Columbia University Irving Medical Center, shared a post on LinkedIn about a recent article by Leslie Skeith et al, adding:

“This visual outlines how estrogen, progesterone, and testosterone affect coagulation pathways, platelet activity, red blood cells, and vascular function.

These physiologic changes can alter clotting risk depending on dose, formulation, and patient specific factors.

Recent evidence highlights the importance of evaluating individual risk, including prior thrombosis, underlying conditions, and treatment indication when considering hormone therapy.

Clear understanding of these mechanisms supports safer clinical decision making across cardiology, internal medicine, and women’s health.

Follow Zain Khalpey for more on AI and Healthcare.”

Title: Sex Hormone Influences on Venous Thrombotic and Cardiovascular Risk

Authors: Leslie Skeith, Shannon M. Bates

Zain Khalpey: The Hidden Impact of Sex Hormones on Thrombosis and Heart Health

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