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Low-Dose Aspirin Reduces Colorectal Cancer Recurrence in PIK3CA-Mutated Patients
Flora Peyvandi/X
Sep 20, 2025, 15:45

Low-Dose Aspirin Reduces Colorectal Cancer Recurrence in PIK3CA-Mutated Patients

Flora Peyvandi, Professor of Internal Medicine-Hemostasis and Thrombosis Unit, University of Milan, former President of ISTH, shared on X:

“Low dose Aspirin led to a significantly lower incidence of colorectal cancer recurrence than placebo among patients with PIK3CA hotspot mutations in exon 9 or 20 and with a similar benefit among those with other somatic alterations in PI3K pathway genes.”

Title: Low-Dose Aspirin for PI3K-Altered Localized Colorectal Cancer

Authors: Anna Martling, Ida Hed Myrberg, Mef Nilbert, Henrik Grönberg, Fredrik Granath, Martin Eklund, Tom Öresland, Lene H. Iversen, Carola Haapamäki, Martin Janson, Karin Westberg, Josefin Segelman, Urban Ersson, Mattias Prytz, Eva Angenete, Rebecka Bergström, Markus Mayrhofer, Bengt Glimelius, Johan Lindberg

Aspirin

Read the full article here.

Find more on Hemostasis Today.

Anna Martling Bengt Glimelius Carola Haapamäki colorectal cancer Eva Angenete Flora Peyvandi Fredrik Granath Hematology Hemostasis Today Henrik Grönberg Ida Hed Myrberg Johan Lindberg Josefin Segelman Karin Westberg Lene H. Iversen low-dose aspirin Markus Mayrhofer Martin Eklund Martin Janson Mattias Prytz Mef Nilbert PIK3CA Rebecka Bergström Tom Öresland Urban Ersson
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