Deep Molecular Modeling for Type 2A VWD from Omid Seidizadeh
RPTH Journal shared on LinkedIn:
”Fascinating new study on Type 2A Von Willebrand Disease from Omid Seidizadeh and colleagues.
They identified 15 VWF-A2 domain variants and, using structural modeling, showed how these changes drive bleeding and related complications through multiple distinct mechanisms.
Check it out.
Authors: Luca Mollica, David Giana, Luciano Baronciani, Paolo Colpani, Lea Sicuro, Andrea Cairo and Flora peyvandi”
Read the full article here.
Article: Deep molecular modeling and mechanistic insights into type 2A von Willebrand disease with von Willebrand factor A2 domain mutations
Authors: Omid Seidizadeh, Luca Mollica, Davide Giana, Luciano Baronciani, Paola Colpani, Lea Sicuro, Andrea Cairo, Flora Peyvandi
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