Jan Sloves: Venous Phasicity and the Role of IVC Mechanics
Jan Sloves, President and Consultant at Vascular Imaging Professionals LLC, shared a post on LinkedIn about a recent article by Seshadri Raju et al, adding:
“We were all taught that venous phasicity comes from the thoraco‑abdominal pump: negative intrathoracic pressure ‘pulls,’ rising intra‑abdominal pressure ‘pushes.’
Raju et al’s new JVSVL 2026 paper makes a strong case that this story is incomplete
In 20 healthy volunteers plus 55 routine echo patients, they show:
- Superior vena cava territory (IJV, subclavian, axillary) has continuous, non‑phasic flow throughout respiration
- Inferior vena cava territory (IVC and lower limb tributaries) shows expiratory‑dominant phasic flow, often with minimal or absent inspiratory flow
- The short thoracic IVC stenoses with inspiration (approximately 30% diameter reduction, sometimes near‑collapse), while the suprarenal abdominal IVC dilates by approximately 35% on IVUS – so much for the classic ‘abdominal pump’
Central venous pressures in the IVC/SVC remain positive in both inspiration and expiration and are higher during expiration, which does not fit a simple inspiratory suction‑pump model
The authors argue this is really an IVC deformation phenomenon.
As the diaphragm descends, it traction‑stenoses the thoracic IVC and lets the upper abdominal IVC balloon.
Both deformities create turbulence, disrupt laminar flow, and transiently reduce IVC flow – hence the expiratory – dominant phasic signal we rely on in the lab
Bottom line: phasicity looks like a unique mechanical behavior of the IVC and its tributaries, not a global thoraco‑abdominal pump.
SVC tributaries stay mostly clean.
Interesting paper – what are your thoughts?”
Title: Venous Flow Phasicity Is Not Caused by the Thoraco-Abdominal Pump, But Results from Luminal Deformation of the Inferior Vena Cava Caused by Respiratory Diaphragmatic Movement.
Authors: Seshadri Raju, Sarah Kendrick, Reuben Harper Stone, Taimur Saleem
Read the Full Article on Journal of Vascular Surgery: Venous and Lymphatic Disorders
Other articles featuring Jan Sloves on Hemostasis Today.
-
Sep 29, 2026, 16:35Jonathan Douxfils: Navigating the VTE Risk Continuum in Reproductive Medicine
-
Sep 29, 2026, 16:35Chaima Rajeh: Types of Anemia and Their Laboratory Features
-
Sep 29, 2026, 16:27Scott Isaacs: How GLP-1 RAs Target Systemic Inflammation to Drive Cardio, Autoimmune, and Gut Health
-
Sep 29, 2026, 16:21Yitshak Kreiss: From Treating Patients to Defining the Standard of Knowledge
-
Sep 29, 2026, 16:18Edward Lee Carter: Why Periprocedural DOAC Guidance Needs a Common Output Standard
-
Sep 29, 2026, 16:07Yasmine Laraba: Deep Vein Thrombosis Causes, Signs and Management
-
Sep 29, 2026, 16:01Stephen Cornelissen: How Joining the Stem Cell Registry Can Save Patients with Blood Cancers
-
Sep 29, 2026, 15:45Alan Nurden: Could Mast Cell aIIb Integrin Play a Key Role in Septic Thrombus Stability?
-
Sep 29, 2026, 15:43Priyadarshani Sharma: Advocacy and Patient Rights Transform Indian Haemoglobinopathies Care