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Fibrinogen-Guided Management of Postpartum Hemorrhage – Transfusion Medicine KMC Manipal
Mar 22, 2026, 16:03

Fibrinogen-Guided Management of Postpartum Hemorrhage – Transfusion Medicine KMC Manipal

Transfusion Medicine KMC Manipal shared a post on LinkedIn about a recent article by Ganesh Mohan et al, adding:

“Postpartum haemorrhage (PPH) continues to claim approximately 70,000 maternal lives annually, especially in resource-limited settings.

In this study, we explored how goal-directed bleeding management (GDBM) can transform outcomes by prioritizing fibrinogen correction.

This study reflects challenges unique to LMIC settings-delayed referrals, geographic barriers, and limited access to fibrinogen concentrates.

Key Findings:

  • Higher fibrinogen correction with GDBM (Increase of 74% vs 55%)
  • 43% reduction in cryoprecipitate turnaround time
  • Improved coagulopathy resolution (26.2% to 7.4%)”

Title: Early cryoprecipitate transfusion through goal-directed bleeding management in a real world setting – How important it is to focus on the fibrinogen in major obstetric Haemorrhage

Authors: Ganesh Mohan, Shamee Shastry, Prethika P. A., Deepika Chenna, Bemma Paonam

Read the Full Article on Transfusion Medicine

Fibrinogen-Guided Management of Postpartum Hemorrhage - Transfusion Medicine KMC Manipal

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