Limiaa Babikir: What Is Polyspecific DAT?
Limiaa Babikir, Medical Laboratory Technologist at King Abdulaziz Hospital for National Guard, shared a post on LinkedIn:
“Autoimmune hemolytic anemia (peripheral blood).
Spherocytes are commonly seen on the peripheral blood smear when extravascular immune hemolysis has occurred.
Serum Bilirubin (primarily indirect) and LD are usually elevated, and Urobilinogen may be increased in urine and stool specimens.
The DAT is usually positive.
The DAT (also called the direct antiglobulin test, and previously called the direct Coombs’ test) detects antibody and/or complement coating patient’s red cells.
In the DAT, patient red cells are washed to remove adherent proteins and then reacted with a reagent containing high-titer, polyspecific antibodies against both IgG (all subclasses) and complement, then examined for resulting red cell agglutination.
This is called the polyspecific DAT.”
Stay updated with Hemostasis Today.
-
Jun 26, 2026, 18:28Daniel Pereira Monteiro: Why Is Beta Thalassaemia Major so Severe?
-
Jun 26, 2026, 18:27Pradip Pawar: Cell and Gene Therapy – Transforming Medicine in the 21st Century
-
Jun 26, 2026, 18:26Aviva Schwartz: How Can We Better Protect Patients After an Ischemic Stroke?
-
Jun 26, 2026, 18:25Does Reversing Factor Xa Inhibitors Really Carry as Much Thrombotic Risk as We Think? – RPTH Journal
-
Jun 26, 2026, 18:25Akshat Jain: Novel Therapies in Childhood Blood and Cancer Disorders
-
Jun 26, 2026, 16:57Abdul Muqtadir Abbasi: Anticoagulation in DVT Patients With Hidden Varices Requires Extreme Caution
-
Jun 26, 2026, 16:42Anesa Mulabecirovic: Why Von Willebrand Disease Takes Years to Diagnose in Women
-
Jun 26, 2026, 16:32Kaitlin Lichty: A New Identity Reflecting a Shared Legacy of Bleeding Disorders
-
Jun 26, 2026, 16:07Toong Youttananukorn: The WFH Registry Driving Better Care and Advocacy