Pall T. Onundarson: Frail Elderly Korean Atrial Fibrillation Patients Do Worse If Switched to DOACs in a Nationwide Observational Study
Pall T. Onundarson, Professor Emeritus at Landspitali University Hospital, shared a post on LinkedIn:
“Frail elderly Korean atrial fibrillation patients do worse if switched to DOACs in a nationwide observational study.
This would appear to support the previous RCT of Joosten et al (Circulation. 2024;149:279–289. DOI: 10.1161/CIRCULATIONAHA.123.066485) from Holland.
It should also caution physicians against celebrating convenience over efficacy and safety if they are able to provide quality treatment with warfarin/VKAs.
It would also suggest that warfarin isn´t dead yet as treatment of NVAF – and that working on improved warfarin monitoring and outcomes remains worthwhile, even mandatory, for the benefit of patients.
There is an interesting read in a commentary from Karakasis (Eur Heart J 2026.) – and a rebuttal to that commentary from Lee and Choi (European Heart Journal (2026) 00, 1–2).”
Stay updated with Hemostasis Today.
-
Aug 6, 2026, 17:38Cameron Cook: How Cost-Effective Is Evolocumab for Patients at High Cardiovascular Risk?
-
Aug 6, 2026, 15:46Zain Khalpey: Left Atrial Appendage Closure vs Oral Anticoagulation in Atrial Fibrillation
-
Aug 6, 2026, 15:25Mohd Ashhad: Cryoprecipitate – A Small Blood Component with a Big Clinical Role
-
Aug 6, 2026, 15:19Faris Otmani: New Systematic Review Evaluates TAVR and SAVR in Low-Risk Patients
-
Aug 6, 2026, 15:13How a PERT Team Navigates Severe Pregnancy PE – JTH
-
Aug 6, 2026, 15:05Melissa Hollo: Are All MS Symptoms Really Due to MS?
-
Aug 6, 2026, 15:03Zubair Naimullah: Early Recognition of Deep Vein Thrombosis Can Save Lives
-
Aug 6, 2026, 14:45Leonard Valentino: Why Hemophilic Arthropathy Is More Than an Inflammatory Joint Disease
-
Aug 6, 2026, 14:31Scarlet R. Spain: Early Recognition of Adolescent Cerebral Venous Thrombosis