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Caitlin Raymond: Understanding Risks in Rare Group A Subtypes with Anti-A1 Antibodies in Transfusion Medicine
Caitlin R./LinkedIn
Feb 7, 2026, 15:13

Caitlin Raymond: Understanding Risks in Rare Group A Subtypes with Anti-A1 Antibodies in Transfusion Medicine

Caitlin Raymond, Assistant Professor of Pathology and Transfusion Medicine at the University of Wisconsin-Madison, shared a post on LinkedIn:

”In transfusion medicine, some risks feel larger than they actually are — not because they’re common, but because the evidence we have is skewed toward worst-case scenarios.

I recently wrote a follow-up blog post on rare group A subtypes with anti-A1 antibodies, prompted by a real case and a conversation with a reference laboratory.

Case reports tell us what can go wrong. Reference labs see what actually does go wrong — and how often.

This post walks through:

  • When cold reacting anti-A1 actually becomes dangerous
  • Why malignancy-associated cases don’t generalize
  • When to choose group O blood for rare group A subtypes

If you’ve ever felt uneasy making decisions where the literature offers warnings but no denominator, this one’s for you.”

Caitlin Raymond: Understanding Risks in Rare Group A Subtypes with Anti-A1 Antibodies in Transfusion Medicine

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