Hemostasis Today

February, 2026
February 2026
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Hugh Kearney: Highlighting the Relevance of the Inflammasome in Multiple Sclerosis Pathophysiology
Feb 19, 2026, 14:00

Hugh Kearney: Highlighting the Relevance of the Inflammasome in Multiple Sclerosis Pathophysiology

Hugh Kearney, Neurologist at Trinity College Dublin, shared on LinkedIn about a recent article he and his colleagues co-authored, adding:

“I am pleased to be involved in this new study from Eric Downer‘s lab in TCD  – this new paper highlights the relevance of the inflammasome in the pathophysiology of MS.

NLRP3 has previously been highlighted to be of relevance to progression in MS and our study supports this.”

Title: Elevated expression of the NLRP3 inflammasome in post-mortem brain white matter and immune cells in multiple sclerosis

Authors: Almudena Otálora-Alcaraz, Melody Cui Sun, Nicole Hofman, Lisa Costelloe, Hugh Kearney, Jack A. Prenderville, Eric J. Downer

Read the Full Article on Multiple Sclerosis and Related Disorders.

Hugh Kearney: Highlighting the Relevance of the Inflammasome in Multiple Sclerosis Pathophysiology

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