Limiaa Babikir: What Is Polyspecific DAT?
Limiaa Babikir, Medical Laboratory Technologist at King Abdulaziz Hospital for National Guard, shared a post on LinkedIn:
“Autoimmune hemolytic anemia (peripheral blood).
Spherocytes are commonly seen on the peripheral blood smear when extravascular immune hemolysis has occurred.
Serum Bilirubin (primarily indirect) and LD are usually elevated, and Urobilinogen may be increased in urine and stool specimens.
The DAT is usually positive.
The DAT (also called the direct antiglobulin test, and previously called the direct Coombs’ test) detects antibody and/or complement coating patient’s red cells.
In the DAT, patient red cells are washed to remove adherent proteins and then reacted with a reagent containing high-titer, polyspecific antibodies against both IgG (all subclasses) and complement, then examined for resulting red cell agglutination.
This is called the polyspecific DAT.”
Stay updated with Hemostasis Today.
-
Jun 23, 2026, 23:05Rounak Dubey: ISBT Academy Session on Agentic AI
-
Jun 23, 2026, 22:59Mohammed Maher Babiker: When ‘Low Platelets’ aren’t Really Low
-
Jun 23, 2026, 22:49Giovanni Merlino: Why Does Stress Hyperglycemia Worsen Stroke Outcomes?
-
Jun 23, 2026, 22:41Tareq Abadl: Coombs Test – The Key to Detecting Immune-Mediated Hemolysis
-
Jun 23, 2026, 22:32How WFH Impacted the Bleeding Disorders Community in 2025
-
Jun 23, 2026, 22:03Erin VanDyke: A Journey Through VTE Leadership and Healthcare Transformation
-
Jun 23, 2026, 21:19Ahmed Koriesh: Join Us for Future of Stroke Care 2026
-
Jun 23, 2026, 20:30Aladdin Mohammad: Baseline IgG as a Key Predictor of Hypogammaglobulinaemia in AAV
-
Jun 23, 2026, 19:20Simos Kokkovos: 1st Ever Mobile Stroke Unit in Greece is on its way to Metropolitan Hospital