Limiaa Babikir: What Is Polyspecific DAT?
Limiaa Babikir, Medical Laboratory Technologist at King Abdulaziz Hospital for National Guard, shared a post on LinkedIn:
“Autoimmune hemolytic anemia (peripheral blood).
Spherocytes are commonly seen on the peripheral blood smear when extravascular immune hemolysis has occurred.
Serum Bilirubin (primarily indirect) and LD are usually elevated, and Urobilinogen may be increased in urine and stool specimens.
The DAT is usually positive.
The DAT (also called the direct antiglobulin test, and previously called the direct Coombs’ test) detects antibody and/or complement coating patient’s red cells.
In the DAT, patient red cells are washed to remove adherent proteins and then reacted with a reagent containing high-titer, polyspecific antibodies against both IgG (all subclasses) and complement, then examined for resulting red cell agglutination.
This is called the polyspecific DAT.”
Stay updated with Hemostasis Today.
-
Nov 8, 2026, 19:31Anna Kajaste-Rudnitski: Presenting AAV-Induced p53 Signalling in Human CNS Cells at ESGCT 26
-
Nov 8, 2026, 19:29David McIntosh: Cybersecurity Matters, but Blood Availability Remains the Bigger Challenge
-
Nov 8, 2026, 19:26Wenxue Ma: An Integrative Framework for Macrophage-Mediated Therapeutic Resistance in Cancer
-
Nov 8, 2026, 19:25Yildiz Yigit: Presenting a Polycythemia Vera Case at the MPN Subcommittee Session
-
Nov 8, 2026, 18:56Denis Oduor: Strengthening the Regulation and Delivery of Blood Transfusion and Transplantation Services
-
Nov 8, 2026, 18:28Raghavendra Rao: A Narrative Review on Chronic Venous Disease during Pregnancy
-
Nov 8, 2026, 17:57Dhiren Patel: PLD1-Derived Phospholipids Regulate NAD Kinase and ROS Production in Neutrophils
-
Nov 8, 2026, 17:48Andra T.: What Causes Antiphospholipid Syndrome? – Four Steps, not One Cause
-
Nov 8, 2026, 17:38Nasrin Samadi: Can a Normal Clotting Test Be Misleading?