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Stéphanie Forté: New Insights on Stroke in Adults with Sickle Cell Disease
Stéphanie Forté and Jonathan St-Onge
Feb 19, 2026, 14:07

Stéphanie Forté: New Insights on Stroke in Adults with Sickle Cell Disease

Stéphanie Forté, Medical Lead of the Red Blood Cell Disorders Comprehensive Centre (SANGRE) at CHUM, shared a post on LinkedIn about a recent article she and her colleagues co-authored, published in The British Journal of Haematology, adding:

“Stroke and Sickle Cell Disease: A Montreal Study Highlights Lasting Impacts in Adults

The British Journal of Haematology publishes a study led by our team at University of Montreal Health Centre (CHUM), the CHUM Research Centre, and the University of Montreal, shedding light on an underrecognized reality: stroke in adults living with sickle cell disease (SCD).

Sickle cell disease is a genetic blood disorder that primarily affects individuals of African and Caribbean descent.

While stroke risk is well established in children, much less is known about its impact in adults.

In a cohort of 454 adults followed at CHUM, we found that nearly 1 in 20 had experienced a stroke.

Importantly, these events were not limited to the most severe genotypes, but also occurred in forms often perceived as ‘milder.’

The consequences are often long-lasting:

  • cognitive impairment (memory and attention)
  • reduced functional independence

This work reflects a strong multidisciplinary collaboration between researchers in hematology, vascular neurology (ICranium), and highly engaged trainees.

Special recognition to Jonathan St-Onge, future hematology resident at Université de Montréal, for his teamwork, perseverance, and dedication to advancing care and research.

‘Sickle cell disease is a lifelong condition, and its neurological complications in adulthood remain underrecognized and require greater attention.’

Our findings highlight the need for:

  • improved stroke prevention strategies in SCD
  • early recognition of neurological symptoms
  • specialized, structured care for adults

This work also contributes to a broader effort to address health inequities — a key focus of Black History Month.”

Title: Stroke burden and functional impacts in adults with sickle cell disease

Authors: Jonathan St-Onge, Tzvetena Hristova, Chrystelle Charles, Olena Bereznyakova, Gregory Jacquin, Olivier Pouliot, Janick Caron-Lecuyer, Mia Stevanovik, Sara-Maude Desforges, Costa M. Kazadi, Julian Alejandro Rivillas, Christian Stapf, Stéphanie Forté

Read the Full Article on The British Journal of Haematology

 

Stéphanie Forté: New Insights on Stroke in Adults with Sickle Cell Disease

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Christian Stapf Chrystelle Charles Costa M. Kazadi Gregory Jacquin Health Hematology Hemostasis Hemostasis News Hemostasis Today Janick Caron-Lecuyer Jonathan St-Onge Julián Alejandro Rivillas Medicine Mia Stevanovik Olena Bereznyakova Olivier Pouliot Sara-Maude Desforges SCD Sickle Cell Disease Stéphanie Forté stroke The British Journal of Haematology thrombosis Tzvetena Hristova
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