Arno Nierich: How Caffeine Affects Red Blood Cells and Blood Storage
Arno Nierich, Anaesthesiologist and Intensivist specializing in cardiac surgery at Isala Hospital, shared a post on LinkedIn:
”Caffeine, a non-selective antagonist of the ADORA2B receptor found on red blood cells (RBCs), appears to interfere with key metabolic and hypoxic responses, including glycolysis and 2,3-BPG synthesis, both essential for oxygen delivery under stress.
These findings suggest that caffeine may compromise ATP production and increase hemolysis during storage.
Why This Matters for Innovation in Blood Transfusion
By enabling autologous blood recovery and bedside reinfusion, HemoClear supports PBM strategies that eliminate the need for extended storage, thereby avoiding biochemical degradation risks linked to factors like caffeine exposure.
As we deepen our understanding of how lifestyle and genetics influence transfusion outcomes, it’s also time to rethink how we approach blood safety, quality, and innovation.”
Find more information here.
Stay updated with Hemostasis Today.
-
Dec 6, 2025, 18:02ASH25 Day 1: Don’t Miss The Highlights
-
Dec 6, 2025, 15:44Atul Gupta on Where The Healthcare Innovation is Headed
-
Dec 6, 2025, 15:22Nathan White on How Inflammation Contributes to Coagulopathy After Trauma
-
Dec 6, 2025, 15:02Anas Younes on AstraZeneca’s Aims in Blood Cancer to Be Presented at ASH25
-
Dec 6, 2025, 14:08David Alderman: ASH25 is Live
-
Dec 6, 2025, 13:53Isabelle Mahé Presents The Proposals from INNOVTE CAT Working Group
-
Dec 6, 2025, 11:50Steve Tuplin on Roche’s Mission at ASH25
-
Dec 6, 2025, 11:13Khaled Musallam on The Lancet Haematology Podcast: Your ASH25 Roadmap
-
Dec 5, 2025, 03:46Sreeni Sivan Pillai: Preventing Thrombophlebitis and Upper Limb DVT in PICC Lines