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Arun V. J: Artificial Blood Is Closer Than You Think
Oct 23, 2025, 09:57

Arun V. J: Artificial Blood Is Closer Than You Think

Arun V J, Consultant in the Department of Transfusion Medicine at Malabar Medical College, shared a post on LInkedIn:

”Scientists Are Creating Blood in the Lab (Artificial Blood) — and It Might Save Millions
Every few seconds, somewhere in the world, someone needs blood.
And every year, thousands die waiting for it.

Even today, despite thousands of donation drives, the demand for blood far exceeds supply.
That’s when science decided to do what humans couldn’t — create blood in the lab.
Sounds like science fiction? It’s not.

It’s called Artificial Blood, and it’s one of the most fascinating frontiers in modern medicine.

Here’s how it works

  • Artificial blood isn’t real blood.
  • It’s a lab-made oxygen carrier — designed to do one job: deliver oxygen to your tissues when real blood isn’t available.

There are two major scientific approaches:

  1. Hemoglobin-Based Oxygen Carriers (HBOCs) — purified and modified hemoglobin (from human or bovine sources) that can circulate safely without red blood cells.
  2. Perfluorocarbon-Based Emulsions (PFCs) — synthetic molecules that physically dissolve and carry oxygen, much like soda holds carbon dioxide.

These substitutes are chemically sterile, don’t need cross-matching, and have shelf lives measured in months — not weeks.

Imagine this:

  • A road accident victim gets an infusion that keeps them alive until real blood arrives.
  • A soldier injured on a battlefield receives a blood substitute instantly.
  • A rural hospital in India no longer faces panic due to blood shortages.

Artificial blood could make all this possible.

But — the science is still evolving.
Early trials showed side effects like vessel constriction and oxidative stress.
Now, researchers are using nanotechnology, stem cells, and even AI modeling to design safer, smarter versions.
The cost might be too high that it may not be accessible to everyone.

Some promising names to watch:

  • HEMARINA – uses marine worm hemoglobin (Hemo2life)
  • KaloCyte, Inc. aloCyte (USA) – developing ErythroMer, a synthetic red cell substitute
  • FluorO2 Therapeutics – creating oxygen-rich emulsions for trauma care

The vision?
To build an emergency-ready, shelf-stable oxygen carrier that no longer depends on human donors.

As a doctor in transfusion medicine, I’ve seen what blood means — and what happens when it’s missing.

If science can bridge that gap, we’re looking at a future where no patient dies because a donor wasn’t available in time.

That’s not science fiction.
That’s science catching up with compassion.

Read the full article — in simple, clear language — on my blog:

What do you think?
Will artificial blood redefine healthcare — or will real blood donors always remain irreplaceable?”

Title: Artificial Blood Is Closer Than You Think: How Science Is Rewriting the Future of Saving Lives

Author: Arun V J

Artificial Blood

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