Breakthrough in Blood: Cécile Denis and INSERM Team Develop Nanobody Therapy for Type 1 VWD
Cécile Denis, director of research at INSERM, shared a post on LinkedIn:
”The result of an almost 10-year journey: a bispecific nanobody bridging von Willebrand factor to albumin in order to prolong the half-life of VWF and increasing its plasma levels. A potential treatment for patients with decreased VWF levels (Type 1 VWD).
We should not forget that Von Willebrand disease remains largely underestimated and therefore untreated, especially in type 1 patients.
Thank you Ivan Peyron, Caterina Casari, Geneviève McCluskey, Stéphanie Roullet, Vincent Licari, Emilie BOCQUET, Claire Auditeau, Melanie Daniel, sophie susen, Olivier Christophe, Peter Lenting, HITh lab Inserm, INSERM, ANR Agence nationale de la recherche.”
Read the full study here.
Title: A bispecific nanobody for the treatment of von Willebrand disease type 1
Authors: Ivan Peyron, Caterina Casari, Genevieve McCluskey, Stéphanie Roullet, Vincent N Licari, Emilie Bocquet, Claire Auditeau, Melanie Y Daniel, Sophie Susen, Olivier D. Christophe, Peter J Lenting, Cécile V. Denis
Stay updated with Hemostasis Today.
-
Sep 11, 2026, 03:10Chris Oung: Anticoagulation for Atrial Fibrillation with Intermediate Stroke Risk
-
Sep 10, 2026, 21:33J. Meireles-Brandao: Lp(a)HORIZON and the Role of Inflammation in ASCVD
-
Sep 10, 2026, 21:31Alejandro González Veliz: Pregnancy is a Cardiovascular Stress Test
-
Sep 10, 2026, 21:30Tareq Abadl: Did You Know That the Type of Hemoglobin in Our Blood Changes Throughout Life?
-
Sep 10, 2026, 21:30Sumyea Kabir: Apheresis Awareness Day – One Donor, One Procedure, One Therapeutic Difference
-
Sep 10, 2026, 21:30Suhasini Sil: Excited to Share Our New Publication on HLA Beyond Histocompatibility
-
Sep 10, 2026, 21:29Michael Meneghini: Your Calves Are Not Just for Walking
-
Sep 10, 2026, 21:27One month until International Plasma Awareness Week – PPTA Europe
-
Sep 10, 2026, 21:26John Strouse: Supporting Research to Improve Lives in Sickle Cell Disease