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Bruno Pougault on the Limitations of DOACs in High-Risk Conditions
Bruno Pougault/LinkedIn
Nov 22, 2025, 16:17

Bruno Pougault on the Limitations of DOACs in High-Risk Conditions

Bruno Pougault, Global Marketing Hemostasis Product Manager at HORIBA, shared on LinkedIn:

”DOACs may not be as efficacious or as safe as the current standard of care in conditions such as mechanical heart valves, thrombotic antiphospholipid syndrome, and atrial fibrillation associated with rheumatic heart disease”

Read the full article here.

Article: When Direct Oral Anticoagulants Should Not Be Standard Treatment: JACC State-of-the-Art Review

Authors: Antoine Bejjani, Candrika D. Khairani, Ali Assi, Gregory Piazza, Parham Sadeghipour, Azita H. Talasaz, John Fanikos, Jean M. Connors, Deborah M. Siegal, Geoffrey D. Barnes, Karlyn A. Martin, Dominick J. Angiolillo, Dawn Kleindorfer, Manuel Monreal, David Jimenez, Saskia Middeldorp, Mitchell S. V. Elkind, Christian T. Ruff, Samuel Z. Goldhaber, Harlan M. Krumholz, Roxana Mehran, Mary Cushman, John W. Eikelboom, Gregory Y. H. Lip, Jeffrey I. Weitz, Renato D. Lopes, Behnood Bikdeli

Bruno Pougault on the Limitations of DOACs in High-Risk Conditions

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AFib Ali Assi Antiphospholipid Syndrome Antoine Bejjani APS Atrial Fibrillation Azita H. Talasaz Behnood Bikdeli Bruno Pougault Candrika D Khairani Christian T. Ruff David Jimenez Dawn Kleindorfer Deborah M. Siegal DOACs Dominick J. Angiolillo Geoffrey D. Barnes Gregory Piazza Gregory Y.H. Lip Harlan M. Krumholz Health Hematology Hemostasis Hemostasis Today Jean M. Connors Jeffrey I. Weitz John Fanikos John W. Eikelboom Karlyn A. Martin Manuel Monreal Mary Cushman Mechanical Heart Valves Medicine Mitchell S.V. Elkind Parham Sadeghipour Renato D. Lopes rheumatic heart disease Roxana Mehran Samuel Z. Goldhaber Saskia Middeldorp thrombosis
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