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Mattia Galli: Sex-related Differences in Platelet Reactivity in Patients Both On and Off Antiplatelet Therapy
Mattia Galli/LinkedIn
Aug 20, 2025, 14:25

Mattia Galli: Sex-related Differences in Platelet Reactivity in Patients Both On and Off Antiplatelet Therapy

Mattia Galli, Assistant Professor at Sapienza Università di Roma, Associate Editor of European Heart Journal, shared a proud post on LinkedIn:

”Sex-related differences in platelet reactivity are emerging as a relevant factor in patients both on and off antiplatelet therapy.

In these two recent contributions, published almost simultaneously, we present evidence from both randomized controlled trials and the largest pharmacodynamic study in this setting to date, suggesting that females may benefit from antiplatelet regimens different from those typically used in males.

This represents another important step forward in advancing precision medicine in cardiology.”

Read the full articles in European Heart Journal and EHJ Cardiovascular Pharmacotherapy.

Article 1: Sex differences in dual antiplatelet therapy de-escalation strategies after percutaneous coronary intervention: a network meta-analysis

Authors: Giovanni Occhipinti , Claudio Laudani , Mattia Galli , Luis Ortega-Paz , Vijay Kunadian , Guiomar Mendieta , Riccardo Rinaldi , Felicita Andreotti , Roxana Mehran , Teresa López-Sobrino , Davide Capodanno , Dominick J Angiolillo , Manel Sabaté Tenas , Salvatore Brugaletta

Article 2: Sex-related variations in platelet reactivity in presence or absence of antiplatelet therapy

Authors: Mattia Galli , Sergio Terracina , Eleonora Schiera , Simone De Corci , Diego Sangiorgi , Massimo Mancone , Luigi Frati , Sebastiano Sciarretta , Dominick J Angiolillo , Fabio M Pulcinelli

Mattia Galli: Sex-related Differences in Platelet Reactivity in Patients Both On and Off Antiplatelet Therapy

Stay updated on all science in the field of platelet disorders with Hemostasis Today.

Antiplatelet Therapy Claudio Laudani Davide Capodanno Diego Sangiorgi Dominick J. Angiolillo EHJ Cardiovascular Pharmacotherapy Eleonora Schiera European Heart Journal Fabio M Pulcinelli Felicita Andreotti Giovanni Occhipinti Guiomar Mendieta Health Hematology Hemostasis Today Luigi Frati Luis Ortega-Paz Manel Sabaté Tenas Massimo Mancone Mattia Galli Medicine Platelet disorders Platelet Reactivity Precision Medicine Riccardo Rinaldi Roxana Mehran Salvatore Brugaletta Sebastiano Sciarretta Sergio Terracina Sex-related differences Simone De Corci Teresa López-Sobrino Vijay Kunadian
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