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Arterial or Atypical Clots? Think APLS, PNH, and MPN
Allison Fitzgerald, MD, PhD/X
Dec 19, 2025, 11:34

Arterial or Atypical Clots? Think APLS, PNH, and MPN

Allison Fitzgerald, Heme/Onc Fellow at Dana-Farber, posted on X:

”Today I learned that while clots in veins can be caused by all sorts of things, clots in arteries are usually caused by cancer or anti-phospholipid syndrome (APLS).

Adding paroxysmal nocturnal hemoglobinuria and myeloproliferative neoplasms (which is a subtype of cancer, but more specific, I suppose) to this list.

So clots in arterial or weird venous places:
– APLS
– PNH
– MPN
– HIT
– hyperhomocysteinemia”

 

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Allison Fitzgerald Antiphospholipid Syndrome APLS APS Arterial thrombosis Blood Clot Cancer Associated Thrombosis Dana-Farber Health Hematology Hemostasis Hemostasis Today heparin-induced thrombocytopenia HIT Hyperhomocysteinemia Medicine MPN myeloproliferative neoplasms paroxysmal nocturnal hemoglobinuria PNH thrombosis
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