Fresh Frozen Facts Part 2: A Thoughtful Look at Plasma Transfusion by Dr. Caitlin Raymond
Caitlin Raymond, MD/PhD shared an insightful chain of posts on LinkedIn:
”Fresh Frozen Facts, Part II: FFP Is Not a Vitamin
Too often, fresh frozen plasma (FFP) is ordered as a reflex — for an elevated INR, a vague sense of bleeding risk, or simply because “it can’t hurt.”
But FFP is not a vitamin. It’s a powerful therapy with specific indications, real risks, and limited benefit when used indiscriminately.
In Part II of my plasma product series, I walk through the actual clinical scenarios where plasma works — from TTP and DIC to massive transfusion protocols and rare factor deficiencies.
We also touch on cryopoor plasma, the nuances of thawed plasma shelf life, and the essential question:
Are you treating a true factor deficiency — or just the labs?”
Read the full post here.
Caitlin Raymond, MD/PhD, has launched an educational series on Fresh Frozen Plasma (FFP), now available on her journal blog.
Enjoy the second part and make sure you do not miss all the Fresh Frozen Facts!

Stay tuned for updates to the series on Hemostasis Today.
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Dec 18, 2025, 17:13Daria Camilli on EuroBloodNet and EHC Collaboration for Bleeding Disorders
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Dec 18, 2025, 16:50Marie Cambot on Innovhem’s Quantification of The HbF/HbS Ratio for SCD
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Dec 18, 2025, 16:26Yogesh Rathod on Hematological Issues and ICU
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Dec 18, 2025, 16:09Carlos Doti: I’m Reminded Why ASH is Such a Powerful Close to The Year
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Dec 18, 2025, 15:23Michael Hadley: Well-Timed ACC Statement Just Out in JACC Journals
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Dec 18, 2025, 15:12Wolfgang Miesbach on Insights from Guy Young’s ASH2025 Session on Next-Generation Gene Therapy
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Dec 18, 2025, 14:15Plasma-Derived Therapy for Hemophilia in The Updated European Medicines Agency’s Union List
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Dec 18, 2025, 13:55Laurent Bertoletti: BAT-VTE is One of 7 Projects Funded Under the EFFECT Trial Call!
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Dec 18, 2025, 13:34Alexandru Stieber Explores VEXAS Syndrome
