Fresh Frozen Facts Part 2: A Thoughtful Look at Plasma Transfusion by Dr. Caitlin Raymond
Caitlin Raymond, MD/PhD shared an insightful chain of posts on LinkedIn:
”Fresh Frozen Facts, Part II: FFP Is Not a Vitamin
Too often, fresh frozen plasma (FFP) is ordered as a reflex — for an elevated INR, a vague sense of bleeding risk, or simply because “it can’t hurt.”
But FFP is not a vitamin. It’s a powerful therapy with specific indications, real risks, and limited benefit when used indiscriminately.
In Part II of my plasma product series, I walk through the actual clinical scenarios where plasma works — from TTP and DIC to massive transfusion protocols and rare factor deficiencies.
We also touch on cryopoor plasma, the nuances of thawed plasma shelf life, and the essential question:
Are you treating a true factor deficiency — or just the labs?”
Read the full post here.
Caitlin Raymond, MD/PhD, has launched an educational series on Fresh Frozen Plasma (FFP), now available on her journal blog.
Enjoy the second part and make sure you do not miss all the Fresh Frozen Facts!

Stay tuned for updates to the series on Hemostasis Today.
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Mar 16, 2026, 15:08Mohamed Sikkander Abdul Razak: Warning Signs of Vitamin Deficiencies
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Mar 16, 2026, 15:05Kate Thomas: Plasma Donations Drive New Era of Life-Saving Medicines in the UK
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Mar 16, 2026, 14:51Heghine Khachatryan: Hematologic Causes of Cryptogenic Stroke
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Mar 16, 2026, 14:35Simon Senanu: Understanding the Extrinsic Coagulation Pathway
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Mar 16, 2026, 14:27Mahesan Subramaniam: Why Messy Spaces Impact Women’s Stress Levels More Than Men’s
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Mar 16, 2026, 14:21Marlies Alvarenga: Balancing the Scales in Women’s Cardiovascular Health
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Mar 16, 2026, 13:32Filippo Cademartiri: Inflammation vs Cholesterol as Driver of Residual ASCVD Risk