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Gloria Duah: Can a Blood Transfusion Change Your Blood Type?

Gloria Duah/LinkedIn

Jun 8, 2026, 15:23

Gloria Duah: Can a Blood Transfusion Change Your Blood Type?

Gloria Duah, Doctor of Medical Laboratory Science at Komfo Anokye Teaching Hospital, Gender Children and Social Protection Minister of United Nations Youth Association-Ghana (UNYA-GH), shared a post on LinkedIn:

“Can a Blood Transfusion Change Your Blood Type?

The short answer is No, a blood transfusion does not permanently change your blood type.

Your blood type (A, B, AB, or O, and Rh positive or negative) is determined by genes inherited from your parents. These genetic markers are present on your red blood cells and are produced continuously by your body.

So what happens when you receive a blood transfusion?

When donor blood is transfused, those donor red blood cells temporarily circulate in your bloodstream alongside your own cells. For a short period, laboratory tests may detect both your cells and the donor’s cells, creating what we call a mixed-field reaction.

However, donor red blood cells have a limited lifespan. Over time, they are naturally removed from the circulation, and your body continues producing its own red blood cells with your original blood type.

For example….

A person with blood group O receives blood from a compatible donor during a transfusion.

Immediately after the transfusion, both the recipient’s and donor’s red blood cells are present in the bloodstream. But as the donor cells age and are cleared from the body, only the recipient’s own cells remain.

The person’s blood type is still the same as before the transfusion.

Now is there any exception?……mmmh yes

In very rare cases, such as a bone marrow or stem cell transplant, when a patient receives a transplant from a donor with a different blood type, their body produces both their original cells and the donor’s cells

In conclusion, a routine blood transfusion alone does not permanently change your blood type.

Have you ever heard someone say their blood type changed after receiving blood?”

Gloria Duah: Can a Blood Transfusion Change Your Blood Type?