James Harte on Asundexian and Milvexian’s Strong, Dose-dependent Interferences in Coagulation Assays
James Harte, Assistant Lecturer/PhD Candidate on the School of Biochemistry and Cell Biology at University College Cork, proudly reposted from JTH Journal on LinkedIn:
”Delighted to see our work on the laboratory testing of asundexian, milvexian, from the EOLAS Research Group, shared by the Journal of Thrombosis and Haemostasis (JTH).”
JTH Journal shared on LinkedIn:
”Interferences associated with the factor XIa inhibitors asundexian and milvexian in routine and specialized coagulation assays and their removal by activated charcoal-based adsorbents.
This study shows that the emerging FXIa inhibitors asundexian and milvexian produce strong, dose-dependent interferences in coagulation assays — potentially leading to misinterpretation of hemostatic function.
Importantly, activated charcoal–based adsorbents (including DOAC-Stop) effectively removed these interferences, enabling accurate coagulation testing in treated plasma.”
Read the full paper here.
Article: Interferences associated with the factor XIa inhibitors asundexian and milvexian in routine and specialized coagulation assays and their removal by activated charcoal-based adsorbents
Authors: Gavin Buckley, Maeve Crowley, James Harte

Stay updated on all science in the field of coagulation disorders with Hemostasis Today.
-
Aug 26, 2026, 18:14N. Mariana S. Vasquez: From Skin and Gut to Celiac Disease
-
Aug 26, 2026, 18:13Francesca Granata: What Happens When Patients Become Researchers and Researchers Become Advocates?
-
Aug 26, 2026, 18:11Maxima Mendez: Statins Are No Longer the Whole Story
-
Aug 26, 2026, 18:06Ashkan Shoamanesh: ANNEXa-I Analyses Inform Individualized Treatment in Intracranial Hemorrhage
-
Aug 26, 2026, 18:01Sam Tsimikas: Lp(a) and Oxidized Phospholipids Reveal a New Link Between Hypercoagulability and Stronger Clot Formation
-
Aug 26, 2026, 17:52Kamlesh Darji: A Practical Guide to Interpreting Coagulation Tests
-
Aug 26, 2026, 17:46Bruno Pougault: The Hidden Burden of Hemostatic Disorders in Women
-
Aug 26, 2026, 17:39Charan Gubba: Adult ITP – A major shift in the 2026 ASH Guidelines
-
Aug 26, 2026, 17:38Stephan A Mayer: Early Imaging Reveals Higher Risk of Hematoma Expansion After ICH