Sam Tomy K/ LinkedIn
Jun 5, 2026, 02:29
Sam Tomy K.: Antinuclear Antibody Testing and Its Role in Autoimmune Disease Diagnosis
Sam Tomy K, Laboratory Technician at MVR Cancer Centre and Research Institute, shared a post on LinkedIn:
“Understanding the ANA Test — A Key Marker in Autoimmune Diagnostics
The Antinuclear Antibody (ANA) test plays a crucial role in detecting autoimmune disorders such as lupus, Sjögren syndrome, systemic sclerosis, and mixed connective tissue disease.
In the laboratory, ANA testing by indirect immunofluorescence on HEp-2 cells remains the gold standard for identifying autoantibodies and interpreting fluorescence patterns.
Key highlights:
- ANA patterns and their clinical significance
- HEp-2 cell indirect immunofluorescence
- Titer interpretation
- Common autoimmune associations
- Importance of quality control in ANA testing
As medical laboratory professionals, understanding the science behind ANA testing helps improve diagnostic accuracy and patient care.”
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