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Atherosclerosis – How Much Does Fitness Really Add to Cardiovascular Risk Assessment?
Nov 13, 2025, 01:10

Atherosclerosis – How Much Does Fitness Really Add to Cardiovascular Risk Assessment?

Atherosclerosis posted on LinkedIn:

”How much does fitness really add to cardiovascular risk assessment?

In over 2300 adults with zero coronary artery calcium (CAC) from the SCAPIS cohort, higher cardiorespiratory fitness (CRF) was strongly associated with a lower likelihood of hidden atherosclerosis.

Each 1 ml·kg⁻¹·min⁻¹ increase in CRF → 4.5% lower risk
Adding CRF to SCORE → significantly better prediction
Low-CRF men and women → >100% higher prevalence of plaque

Even when CAC = 0, low fitness still matters.

Could CRF become the next vital sign in preventive cardiology?
We’d love to hear your thoughts – how should fitness be integrated into risk models?”

Read the full article here.

Title: Lower cardiorespiratory fitness is associated with coronary artery atherosclerosis in individuals with a zero CAC score – cross-sectional results from SCAPIS

Authors: Frida Griffina, Jonatan Fridolfsson, Daniel Arvidsson, Elin Ekblom-Bak, Örjan Ekblom, Göran Bergström, Mats Börjesson

Atherosclerosis

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