Abeer Alanazi: New Stroke Prevention Without Increased Bleeding Risk
Abeer Alanazi, Senior Clinical Pharmacist at King Fahad Specialist Hospital Dammam, Member of European Stroke Organisation (ESO), shared a post on LinkedIn about a recent article by Mukul Sharma et al. published in NEJM, adding:
“Here’s the biggest thing to happen to secondary stroke prevention since the advent of clopidogrel!!
The phase 3 OCEANIC-STROKE trial
In patients with recent noncardioembolic ischemic stroke or high-risk TIA, asundexian 50 mg and antiplatelet therapy reduced the risk of ischemic stroke vs placebo (6.2% vs 8.4%; HR 0.74; P<0.001)
No increase in major bleeding.”
Title: Asundexian for Secondary Stroke Prevention
Authors: Mukul Sharma, Qiang Dong, Teruyuki Hirano, Scott E. Kasner, Jeffrey L. Saver, Jaime Masjuan, Andrew M. Demchuk, Charlotte Cordonnier, Daniel Bereczki, Georgios Tsivgoulis, Roland Veltkamp, Ivan Staikov, Hee-Joon Bae, Bruce C.V. Campbell, Andrea Zini, I-Hui Lee, Martin Kovar, Robert Mikulik, Robin Lemmens, José M. Ferro, Thompson Robinson, Hanne Christensen, Serefnur Ozturk, Ronen R. Leker, Peter Turcani, Agnieszka Slowik, Pablo Amaya, Fan Kee Hoo, Gian Marco De Marchis, Michael Knoflach, P.N. Sylaja, Jukka Putaala, Jonathan M. Coutinho, H. Bart van der Worp, Evija Miglane, Vaidas Matijošaitis, Arne G. Lindgren, Gisele Sampaio Silva, Else Charlotte Sandset, Saule T. Turuspekova, Pierre Amarenco, Kevin N. Sheth, Eric E. Smith, John W. Eikelboom, Raed A. Joundi, Karleen Schulze, Lizhen Xu, Laura Heenan, Pablo Colorado, Lars Keller, Eva Muehlhofer, Christoph Neumann, Hardi Mundl, Ashkan Shoamanesh
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