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William Aird: A Basic Architecture of Hematology
William Aird/X
Jul 8, 2026, 16:23

William Aird: A Basic Architecture of Hematology

William Aird, Professor of Medicine at Harvard Medical School, shared a post on LinkedIn:

“A Basic Architecture of Hematology

Hematology can seem overwhelming at first.

Anemias. Leukemias. Neutropenia. Thrombocytosis. ITP. Myeloma. Coagulation disorders. Splenomegaly. Lymphadenopathy.

When I teach students and residents, I find it helpful to begin with a simple map.

Start with the major blood compartments:

  • White cells
  • Red cells
  • Platelets
  • Plasma

Then ask a handful of organizing questions:

  • Is there too little or too much?
  • Is the number normal but the function abnormal?
  • Is the process primary (clonal) or secondary (reactive)?
  • Is the clinical problem bleeding or clotting?

This doesn’t capture all of hematology.

But it provides an architecture; a mental framework that makes the details easier to organize and remember.

Every complex discipline becomes more approachable once you have a map.”

William Aird: A Basic Architecture of Hematology

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