William Aird/X
Jul 8, 2026, 16:23
William Aird: A Basic Architecture of Hematology
William Aird, Professor of Medicine at Harvard Medical School, shared a post on LinkedIn:
“A Basic Architecture of Hematology
Hematology can seem overwhelming at first.
Anemias. Leukemias. Neutropenia. Thrombocytosis. ITP. Myeloma. Coagulation disorders. Splenomegaly. Lymphadenopathy.
When I teach students and residents, I find it helpful to begin with a simple map.
Start with the major blood compartments:
- White cells
- Red cells
- Platelets
- Plasma
Then ask a handful of organizing questions:
- Is there too little or too much?
- Is the number normal but the function abnormal?
- Is the process primary (clonal) or secondary (reactive)?
- Is the clinical problem bleeding or clotting?
This doesn’t capture all of hematology.
But it provides an architecture; a mental framework that makes the details easier to organize and remember.
Every complex discipline becomes more approachable once you have a map.”
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